Highlights:

Highlights
Biol Reprod 2008 79: 179. [Full Text] [PDF]  

Embryo:

Anilkumar Bettegowda, Osman V. Patel, Kyung-Bon Lee, Ki-Eun Park, Mohamed Salem, Jianbo Yao, James J. Ireland, and George W. Smith

Identification of Novel Bovine Cumulus Cell Molecular Markers Predictive of Oocyte Competence: Functional and Diagnostic Implications
Biol Reprod 2008 79: 301-309. [Abstract] [Full Text] [PDF] [Supplemental Data]  

Summary: Cumulus cell cathepsins are predictive of and negatively impact oocyte quality

Female Reproductive Tract:

Yuk-Yin Li, Lei Li, Isabel Shui-Shan Hwang, Fai Tang, and Wai-Sum O

Coexpression of Adrenomedullin and Its Receptors in the Reproductive System of the Rat: Effects on Steroid Secretion in Rat Ovary
Biol Reprod 2008 79: 200-208. [Abstract] [Full Text] [PDF]  

Summary: Adrenomedullin is produced in the rat ovary, and it inhibits ovarian steroid release

Gamete Biology:

Vivek Kumar, Venkatesh Kota, and S. Shivaji

Hamster Sperm Capacitation: Role of Pyruvate Dehydrogenase A and Dihydrolipoamide Dehydrogenase
Biol Reprod 2008 79: 190-199. [Abstract] [Full Text] [PDF]  

Summary: Reactive oxygen species generation by pyruvate dehydrogenase complex components dihydrolipoamide dehydrogenase (DLD) and pyruvate dehydrogenase A (PDHA) regulate capacitation.

Jeremi R. Mountjoy, Wei Xu, Dave McLeod, David Hyndman, and Richard Oko

RAB2A: A Major Subacrosomal Protein of Bovine Spermatozoa Implicated in Acrosomal Biogenesis
Biol Reprod 2008 79: 223-232. [Abstract] [Full Text] [PDF] [Supplemental Figures]  

Summary: A RAB2A protein, PT24, assembles as a prominent member of the sperm perinuclear theca after being transported during spermiogenesis on acrosomal vesicles from the trans-side of the Golgi apparatus to the nuclear envelope

Véronique Thimon, Ezéquiel Calvo, Omédine Koukoui, Christine Légaré, and Robert Sullivan

Effects of Vasectomy on Gene Expression Profiling along the Human Epididymis
Biol Reprod 2008 79: 262-273. [Abstract] [Full Text] [PDF] [Supplemental Table 1]  

Summary: Microarray databases show that vasectomy affects differently the transcriptome of the human caput, corpus, and cauda epididymidis

Alan J. Snow, Pawan Puri, Amparo Acker-Palmer, Tewis Bouwmeester, Srinivasan Vijayaraghavan, and Douglas Kline

Phosphorylation-Dependent Interaction of Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein (YWHA) with PADI6 Following Oocyte Maturation in Mice
Biol Reprod 2008 79: 337-347. [Abstract] [Full Text] [PDF]  

Summary: Peptidylarginine deiminase type VI (PADI6) becomes phosphorylated during mouse oocyte maturation and binds to tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein (YWHA) in the mature egg

Loredana Zilli, Roberta Schiavone, Carlo Storelli, and Sebastiano Vilella

Molecular Mechanisms Determining Sperm Motility Initiation in Two Sparids (Sparus aurata and Lithognathus mormyrus)
Biol Reprod 2008 79: 356-366. [Abstract] [Full Text] [PDF]  

Summary: Changes in the ionic and osmotic environment of the sperm cells have been identified as critical external factors that may be responsible for initiating motility in fish spermatozoa

Pei-hsuan Hung, Marion G. Miller, Stuart A. Meyers, and Catherine A. VandeVoort

Sperm Mitochondrial Integrity Is Not Required for Hyperactivated Motility, Zona Binding, or Acrosome Reaction in the Rhesus Macaque
Biol Reprod 2008 79: 367-375. [Abstract] [Full Text] [PDF]  

Summary: Energy from glycolysis but not oxidative phosphorylation is essential to support sperm motility, hyperactivated motility, and protein tyrosine phosphorylation in rhesus macaque.

Male Reproductive Tract:

Pascale Lybaert, Anne Marie Vanbellinghen, Eric Quertinmont, Michel Petein, Sylvain Meuris, and Philippe Lebrun

K_ATP Channel Subunits Are Expressed in the Epididymal Epithelium in Several Mammalian Species
Biol Reprod 2008 79: 253-261. [Abstract] [Full Text] [PDF] [Supplemental Figures]  

Summary: Kir6.2 (KCNJ11) and SUR2 (ABCC9) are expressed in principal cells from mammalian epididymis, suggesting the presence of ATP-sensitive potassium channels in epididymal epithelium

Minireviews:

Kelly A. Cunningham and Kenneth W. Beagley

Male Genital Tract Chlamydial Infection: Implications for Pathology and Infertility
Biol Reprod 2008 79: 180-189. [Abstract] [Full Text] [PDF]  

Summary: Male chlamydial infections are considered a female problem but are equally prevalent in males, can cause upper genital tract disease, and affect male fertility; thus, a vaccine targeting immunity to both male and female genital tracts is essential

Ovary:

Federico Jensen, Miguel A. Willis, Noelia P. Leopardo, María B. Espinosa, and Alfredo D. Vitullo

The Ovary of the Gestating South American Plains Vizcacha (Lagostomus maximus): Suppressed Apoptosis and Corpora Lutea Persistence
Biol Reprod 2008 79: 240-246. [Abstract] [Full Text] [PDF]  

Summary: Healthy corpora lutea persist throughout gestation in L. maximus, with low level of apoptosis and strong immunostaining for antiapoptotic BCL2 protein, indicating an essential need for corpora lutea to maintain pregnancy.

Anom Bowolaksono, Ryo Nishimura, Takuo Hojo, Ryosuke Sakumoto, Tomas J. Acosta, and Kiyoshi Okuda

Anti-Apoptotic Roles of Prostaglandin E2 and F2alpha in Bovine Luteal Steroidogenic Cells
Biol Reprod 2008 79: 310-317. [Abstract] [Full Text] [PDF]  

Summary: PGE2 and PGF2{alpha} play antiapoptotic roles in bovine luteal steroidogenic cells

Shannon M. Fernandez, Aileen F. Keating, Patricia J. Christian, Nivedita Sen, James B. Hoying, Heddwen L. Brooks, and Patricia B. Hoyer

Involvement of the KIT/KITL Signaling Pathway in 4-Vinylcyclohexene Diepoxide-Induced Ovarian Follicle Loss in Rats
Biol Reprod 2008 79: 318-327. [Abstract] [Full Text] [PDF]  

Summary: VCD-induced ovotoxicity in rats is mediated through compromised KIT/KITL signaling, which is critical for follicular survival

Danielle Monniaux, Nathalie di Clemente, Jean-Luc Touzé, Corinne Belville, Charlène Rico, Martine Bontoux, Jean-Yves Picard, and Stéphane Fabre

Intrafollicular Steroids and Anti-Müllerian Hormone During Normal and Cystic Ovarian Follicular Development in the Cow
Biol Reprod 2008 79: 387-396. [Abstract] [Full Text] [PDF]  

Summary: Enhanced growth and steroidogenesis in small antral follicles precede cyst formation in cow ovaries; anti-Mullerian hormone is not a marker of cystic development in cow, but low concentrations in cysts are associated with luteinization

Pregnancy:

Ming-Kwang Shyu, Mei-Chun Lin, Chiung-Hui Liu, Yen-Rong Fu, Jin-Chung Shih, Chien-Nan Lee, Hsiao-Yu Chen, John Huang, Min-Chuan Huang, and Fon-Jou Hsieh

MUC1 Expression Is Increased During Human Placental Development and Suppresses Trophoblast-Like Cell Invasion In Vitro
Biol Reprod 2008 79: 233-239. [Abstract] [Full Text] [PDF]  

Summary: MUC1 expression in syncytiotrophoblasts and numbers of MUC1-positive extravillous trophoblasts increase with gestational age, and MUC1 overexpression suppresses trophoblast-like cell invasion

Philip S. Bridger, Susanne Haupt, Rudolf Leiser, Gregory A. Johnson, Robert C. Burghardt, Hans-Rudolf Tinneberg, and Christiane Pfarrer

Integrin Activation in Bovine Placentomes and in Caruncular Epithelial Cells Isolated from Pregnant Cows
Biol Reprod 2008 79: 274-282. [Abstract] [Full Text] [PDF]  

Summary: Integrin binding is functional in bovine low passage caruncular epithelial cells from pregnant cows according to the co-localization of signaling proteins with integrin β1, and the enhancement of signaling molecule expression and cell proliferation

Ignacio Garcia-Verdugo, Zahra Tanfin, Emmanuelle Dallot, Marie-Josèphe Leroy, and Michelle Breuiller-Fouché

Surfactant Protein A Signaling Pathways in Human Uterine Smooth Muscle Cells
Biol Reprod 2008 79: 348-355. [Abstract] [Full Text] [PDF]  

Summary: SFTPA1 binds to myometrial cells and initiates the activation of signaling events related to human parturition

Gwonhwa Song, M. Carey Satterfield, Jinyoung Kim, Fuller W. Bazer, and Thomas E. Spencer

Gastrin-Releasing Peptide (GRP) in the Ovine Uterus: Regulation by Interferon Tau and Progesterone
Biol Reprod 2008 79: 376-386. [Abstract] [Full Text] [PDF]  

Summary: GRP in the endometrial glands of the ovine uterus is a novel interferon tau-stimulated and progesterone regulated gene.

Reproductive Technology:

Mourad Assidi, Isabelle Dufort, Atef Ali, Mélanie Hamel, Omran Algriany, Steph Dielemann, and Marc-André Sirard

Identification of Potential Markers of Oocyte Competence Expressed in Bovine Cumulus Cells Matured with Follicle-Stimulating Hormone and/or Phorbol Myristate Acetate In Vitro
Biol Reprod 2008 79: 209-222. [Abstract] [Full Text] [PDF]  

Summary: Cumulus cells are essential to oocyte maturation fulfillment through the expression at 6 h of IVM of a set of differentially expressed candidates that could be valuable predictors of oocyte competence

Testis:

Jonci N. Wolff and Neil J. Gemmell

Estimating Mitochondrial DNA Content of Chinook Salmon Spermatozoa Using Quantitative Real-Time Polymerase Chain Reaction
Biol Reprod 2008 79: 247-252. [Abstract] [Full Text] [PDF]  

Summary: Despite spermatozoal differences in morphology, mitochondrial complexity, and life traits between different fertilization systems (external vs. internal), the mtDNA content of spermatozoa appears to be conserved across vertebrates

Donald C. Wilkerson, Lynea A. Murphy, and Kevin D. Sarge

Interaction of HSF1 and HSF2 with the Hspa1b Promoter in Mouse Epididymal Spermatozoa
Biol Reprod 2008 79: 283-288. [Abstract] [Full Text] [PDF] [Supplemental Figures]  

Summary: Novel binding of HSF1 and HSF2 to the Hspa1b promoter in epididymal spermatozoa may promote expression in the one-cell embryo

Wenli Ma, Gary C. Horvath, Malathi K. Kistler, and W. Stephen Kistler

Expression Patterns of SP1 and SP3 During Mouse Spermatogenesis: SP1 Down-Regulation Correlates with Two Successive Promoter Changes and Translationally Compromised Transcripts
Biol Reprod 2008 79: 289-300. [Abstract] [Full Text] [PDF] [Supplemental Table]  

Summary: Downstream promoter shift in spermatocytes explains why prevalent 8.6-kb Sp1 mRNA correlates with diminished level of SP1 protein; SP3 protein also declines sharply during meiosis

Xiaoqin Ye, Michael K. Skinner, Grace Kennedy, and Jerold Chun

Age-Dependent Loss of Sperm Production in Mice via Impaired Lysophosphatidic Acid Signaling
Biol Reprod 2008 79: 328-336. [Abstract] [Full Text] [PDF]  

Summary: Deletion of Lpar1, Lpar2, and Lpar3 in mice produces increased germ cell apoptosis and impaired spermatogenesis

To see an article, click its [Full Text] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.