| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
Biology of Reproduction, Vol 13, 448-452, Copyright © 1975 by Society for the Study of Reproduction
1 Department of Animal Science and Division of Biological Sciences
Cornell University, Ithaca, New York 14853 Bovine corpora lutea and follicles removed from heifers at the 16th or 17th day of the estrous
cycle were sliced and incubated for 2 h at 37°C with Kreb’s-Ringer bicarbonate buffer containing
glucose. The concentration of prostaglandins of the F series (PGF) in unincubated control luteal
tissue was 25.3 ± 5.1 ng/g and increased to 54.8 ± 13 ng/g (P<0.01) during incubation. PGF
concentration increased when either LH or arachidonic acid was added to the medium; net
stimulation on addition of LH amounted to 33.1 ng/g tissue (P<0.01) and in response to
arachidonic acid was 85.2 ng/g (P<0.001). A higher level of PGF was found in follicles (148 ± 36
ng/gm). This level increased to 287.3 ± 63 (P<0.01) in incubated control tissues; when LH or
arachidonic acid (AA) were added to the medium the net stimulated synthesis amounted to 199.7
ng/gm (P<0.01) and 352.7 ng/gm (P<0.001), respectively. Addition of indomethacin to the incubation medium prevented stimulated synthesis in both folhicular and luteal tissues and resulted in
PGF levels that were not significantly different from levels of unincubated control tissues. The data
indicate that the bovine ovary synthesizes PGF in both follicular and luteal tissues. The stimulation
of PGF synthesis by LH provides further evidence that the preovulatory release of LH causes increased PGF synthesis in the ovary leading to increased steroidogenesis and ovulation.
Accepted on July 21, 1975
This article has been cited by other articles:
|
|
 |
|
  K. Shirasuna, T. Shimizu, K.-G. Hayashi, K. Nagai, M. Matsui, and A. Miyamoto Positive Association, in Local Release, of Luteal Oxytocin with Endothelin 1 and Prostaglandin F2alpha During Spontaneous Luteolysis in the Cow: A Possible Intermediatory Role for Luteolytic Cascade Within the Corpus Luteum Biol Reprod, June 1, 2007; 76(6): 965 - 970. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Shirasuna, H. Asaoka, T. J. Acosta, M. P.B. Wijayagunawardane, M. Ohtani, M. Hayashi, M. Matsui, and A. Miyamoto Real-Time Relationships in Intraluteal Release among Prostaglandin F2{alpha}, Endothelin-1, and Angiotensin II During Spontaneous Luteolysis in the Cow Biol Reprod, November 1, 2004; 71(5): 1706 - 1711. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. Shirasuna, H. Asaoka, T. J Acosta, M. P B Wijayagunawardane, M. Ohtani, K.-G. Hayashi, M. Matsui, and A. Miyamoto Real-time dynamics of prostaglandin F2{alpha} release from uterus and corpus luteum during spontaneous luteolysis in the cow Reproduction, August 1, 2004; 128(2): 189 - 195. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 E. K. Inskeep Preovulatory, postovulatory, and postmaternal recognition effects of concentrations of progesterone on embryonic survival in the cow J Anim Sci, January 1, 2004; 82(13_suppl): E24 - 39. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. A. McCracken, E. E. Custer, and J. C. Lamsa Luteolysis: A Neuroendocrine-Mediated Event Physiol Rev, April 1, 1999; 79(2): 263 - 323. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
