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Biology of Reproduction, Vol 13, 61-67, Copyright © 1975 by Society for the Study of Reproduction
1 Department of Anatomy, School of Medicine,
University of Virginia, Charlottesville, Virginia 22901 The testes of adult male rabbits were studied with the light and electron microscopes at
intervals of up to 9 months after vasectomy or a sham operation. No changes were detected in any
rabbits killed at intervals between 2 weeks and 4 months after vasectomy or in 1 of 2 rabbits
prepared 6 months after vasectomy. In one rabbit killed 6 months after operation spermatogenesis
was severely depressed and a spermatic granuloma was present near the epididymis. All 3 rabbits
killed 9 months after vasectomy exhibited a greater than normal number of multinucleate
spermatids, and this condition was most pronounced in one rabbit in which the epididymis and vas
deferens were the most greatly distended of all the vasectomized animals. No changes were
observed in animals that received a sham operation.
Accepted on March 18, 1975
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